The video, part of Winfrey's series "The Oprah Conversation," featured the namesake host encouraging white guests to admit to their racism and insisting that all white people have a "leg up" because of their skin color.
The latest episode of the AppleTV+ series, which featured activist and former NFL player Emmanuel Acho, spoke with white guests about topics such as whiteness, white privilege, and racism.
Sen. Ted Cruz (R-Texas) also took to social media and shared The Blaze's Tuesday reporting on the matter, blasting Winfrey's remarks as "utter, racist BS."
Conservative commentator Wayne Dupree added, "Billionaire Oprah is now shaming white people for all their 'easy success' in life."
Kimberly Klacik, U.S. House candidate from Maryland, added, "Oprah Winfrey trying to profit off of a manufactured racial divide while being a billionaire when so many people are facing eviction is the sort of nonsense #CancelCulture should attack.