The crowd assembled outside the Supreme Court, where Ginsburg is lying in repose, and while at first they were quiet as the president bowed his head, soon they began to shout and jeer.
President Trump and Senate Republicans plan to exercise their constitutional authority and move forward with a Supreme Court nominee despite Ginsburg's last wishes.
"It has been said that Ruth wanted to be an opera virtuoso, but became a rock star instead," Chief Supreme Court Justice John Roberts said.
President Trump plans to announce his nominee to fill the vacancy on the Supreme Court at 5 p.m. Saturday in the Rose Garden of the White House.
"We are going to be having a very exciting Saturday at five o'clock in the Rose Garden, where I'll be putting forth my nominee for Supreme Court Justice," Trump told reporters Wednesday.