The leftover British device had been found during construction work on Tuesday, prompting evacuations from senior residents' homes and partial road, rail and aviation closures.
Unexploded ordnance in Germany - A legacy of the Allied Forces Have many bomb disposal experts have died?
To date, this remains the biggest evacuation for the removal of World War II unexploded ordnance in Germany.
Authorities conducted another big bomb disposal operation in May 2017, with 50,000 residents in the north-western city of Hanover forced to evacuate their homes.
Dresden has seen its fair share of bomb disposals, as the city was heavily bombed by British and US forces towards the end of World War II on February 13, 1945.